Mediterranean cruises deliver ancient glories and modern delights, from Rome’s legendary Colosseum and Dubrovnik’s medieval walls to trend-setting Barcelona. Every day is filled with iconic cityscapes and landmarks, flaxen beaches and remote coastal villages, fresh seafood paired with incredible wine. Spend the day on secluded Ionian isles on Greek cruises or explore Adriatic castles and palaces in Croatia. Our Mediterranean cruise itineraries are carefully curated to give you more options. Take a 7-day roundtrip cruise with a convenient weekend departure or a longer voyage. We also include more overnights at the beginning and end of our itineraries, so you can spend an extra day in cities like Barcelona, Rome and Athens, and use the ship as your hotel. A cruise to the Mediterranean is the best way to experience all that this breathtaking place has to offer. Welcome.
Explore Mediterranean Cruise Ports & Regions
Collectors' Voyages are combined back-to-back itineraries to make your Mediterranean cruise a longer journey. Span continents and oceans and go to more seldom-seen destinations. Relish in more days at sea to unwind and more ports to discover. A Collectors' Voyage lets you unpack once and still see so much of the world.
Featured Mediterranean Cruise Ports
Explore architectural masterpieces, a contemporary art scene and incredible cuisine in the Catalan capital.
Tour ancient ruins, including the Parthenon. Follow a day sightseeing with an open-air concert under the stars.
Civitavecchia (Rome), Italy
Rome is Italy’s beating heart, full of Renaissance cathedrals and piazzas begging for you to sit and sip espresso.
Kotor is a maze of medieval beauty set on a bay with rolling mountains behind it. Walk along the Old City walls all the way up to Kotor’s fortress, where you’ll be treated to an overlook of red-orange rooftops.
Experience Dubrovnik charms on a Croatia cruise, from its red-orange rooftops to vistas of the deep blue Adriatic.
The city that floats on water and highlight of any Italy cruise, Venice needs no further introduction.
Santorini, the jewel in the crown of Greece's Cyclades, is best known as the island with the giant volcanic caldera at its heart.
Featured Mediterranean Shore Excursions
Eat, drink, and live like a local on Mediterranean cruise excursions and FOOD & WINE® tours. Visit a family-owned winery in Greece’s Oia to taste the rich flavors of this renowned region. Go shopping with a chef in a tucked-away charcutería in Barcelona. Or indulge in a night of traditional dancing and drinks. The opportunities are endless.
Ships Sailing the Mediterranean
Add to Your Mediterranean Cruise
Book flights that depart and arrive in time for Mediterranean cruises with Holland America Line Flight Ease®. Find low prices, loads of options, and enjoy flexibility and support should plans change.
Add a Hotel Package
Extend your trip. Add a hotel package to your Mediterranean cruise and indulge in an unforgettable overnight departure or arrival city.
Plan Ground Transportation
There is a lot of ground to cover, we make it easy to schedule transfers between the airport and ship. Arrange ground transportation ahead of time and breeze to and from your Mediterranean cruise.